2021 Classic Lectures in Pathology What You Need to Know Gastrointestinal Pathology

Educational Objectives
At the completion of this CME teaching activity, you should be able to:
• Prepare for colon cancer and universal screening for Lynch syndrome.
• Identify conditions to consider before surgical pathology subspecialty sign-out.
• Discuss the spectrum of gluten-related disorders and current optimum testing for celiac disease.
• Describe the updated epidemiology of cancer risk and Barrett esophagus and the current data on the efficacy of endoscopic surveillance.
• Recognize the major diagnostic pitfalls in the diagnosis of Barrett’s esophagus and Barrett’s-related dysplasia.
• Discuss the more recently recognized variants of ulcerative colitis as well as some of the issues related to diagnosing dysplasia in the setting of IBD.
• Identify some of the major diagnostic issues in the most common colorectal polyps including serrated polyps.
• Discuss the effects of contemporary therapy on the pathology and management of patients with inflammatory bowel disease.
• Describe the role of the pathologist in helping to manage patients with IBD-related dysplasia and neoplasia.
• Apply risk stratification criteria for the prognostication of gastrointestinal stromal tumors.
• Discuss and recognize the succinate dehydrogenase-deficient gastrointestinal stromal tumor and understand the clinical significance of this category of GIST.
• Identify the biliary pattern of injury on liver biopsy.
• Recognize distinguishing features of steatosis from steatohepatitis.
• List the appropriate immunohistochemical work-up of primary liver tumors.
• Develop an understanding of the characteristic histologic features that allow clear separation of the acute and chronic hepatitis patterns.
• Develop an understanding of the normal histology of the intrahepatic biliary system and how it is affected by a variety of cholestatic liver diseases.
• Develop an understanding of the utility of clinical history and laboratory findings in averting misinterpretation of histologic findings in medical liver biopsies.